Information about Actos and bladder cancer.

Doctor warns of pharmaceutical company influence on data in new book

July 16th, 2012

A prominent doctor and former Secretary of the British Association for Psychopharmacology warns of pharmaceutical companies manipulating data in a new book called “Pharmageddon.” Dr. David Healy argues in the book that companies like GlaxoSmithKline and Takeda Pharmaceuticals outsource clinical trials and hide data from health agencies.

Takeda, which manufactures the diabetes medication Actos, is facing an Actos whistleblower lawsuit alleging that the company did not report non-fatal heart failure and other adverse events to the Food and Drug Administration. The company allegedly ordered researchers to mischaracterize clinical data to make it appear safer than a competing drug, Avandia.

Despite Takeda’s initial claims that the drug was safe, Actos was recently linked to serious side effects, including an increased risk of bladder cancer. A study in the British Medical Journal found that the risk of bladder cancer doubles for patients who use the drug for at least two years.

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