The first Actos bladder cancer lawsuit was filed this week on behalf of a Pennsylvania women who was diagnosed with this disease after taking the drug. The Food and Drug Administration warned in June 2011 that patients who take Actos for more than one year or at the highest doses may face an increased risk of being diagnosed with bladder cancer.
The plaintiff in the Pennsylvania Actos lawsuit was diagnosed with bladder cancer in 2009 after taking the drug for over a decade. In her lawsuit, she stated that she may be forced to undergo bladder removal surgery or chemotherapy treatment as a result of her disease.
Following research linking Actos and bladder cancer, health officials in France and Germany ordered the drug pulled from sale in those countries. So far, the FDA has not announced plans to issue an Actos recall.
Actos—once the best-selling diabetes treatment in the US—may lose a significant portion of its market share over concerns that it could cause bladder cancer, some experts have predicted. According to a health expert at the Yale School of Medicine, Actos should only be prescribed to patients after all other diabetes treatment options have been exhausted.